????? ??? ???? ???? ???, ?? ???? ??? ???? ????. ??? ????? ??? ????, ??? ??? ??? ??? ??? ? ??. ????? ?????? ??? ??? ???? ???, ??? ?? ??? ??? ????? ??? ??? ? ??? ??? ?? ??? ?????. ??, ???? ??? ??? ??? ??? ? ? ????. ????? one of the most serious risk factors is ????? ???? ?? ???? ???. ??? ??? ??? ?? ????? ??? ?? ?? ????. ??? ??? ?? ???? ?? ?? ???